Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1361312 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
The discovery, synthesis and biological evaluation of a novel series of 7-isoxazoloquinolines is described. Several analogs are shown to increase ApoA1 expression within the nanomolar range in the human hepatic cell line HepG2.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Olivier Mirguet, Yann Lamotte, Frédéric Donche, Jérôme Toum, Françoise Gellibert, Anne Bouillot, Romain Gosmini, Van-Loc Nguyen, Delphine Delannée, Jonathan Seal, Florence Blandel, Anne-Bénédicte Boullay, Eric Boursier, Sandrine Martin, Jean-Marie Brusq,