Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1361481 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
We herein report the synthesis, biological activity and structure–activity relationship of derivatives of 5,6-dichloro-1-β-d-ribofuranosylbenzimidazole and benzo[d]imidazole. A lead compound 6o demonstrates potent anti-proliferative activity and the ability to induce cancer cell apoptosis.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hamad M. Alkahtani, Abdullahi Y. Abbas, Shudong Wang,