| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1361726 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
Promising synthetic derivatives of macrolactone natural product (−)-A26771B have been designed and synthesized both from semisynthesis and total synthesis. Further optimization led to the first synthesis of macrolactam analogs of (−)-A26771B with improved antibacterial activity and metabolic stability.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sophie Canova, Renaud Lépine, Amber Thys, Anne Baron, Didier Roche,