| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1361738 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Families of 2-arylbenzotriazoles and 2-arylindazoles that show positive effects in screens predictive of endogenous utrophin upregulation have been identified. Synthesis and structure–activity relationships are described leading to compounds with attractive in vitro profiles.
Graphical abstractFamilies of 2-arylbenzotriazoles and 2-arylindazoles that show positive effects in screens predictive of endogenous utrophin upregulation have been identified. Synthesis and structure–activity relationships are described leading to compounds with attractive in vitro profiles.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Authors
Olivier De Moor, Colin R. Dorgan, Peter D. Johnson, Adam G. Lambert, Cristina Lecci, Carole Maillol, Gary Nugent, Séverine D. Poignant, Paul D. Price, Richard J. Pye, Richard Storer, Jonathon M. Tinsley, Richard Vickers, Renate van Well,