| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1361742 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
Naturally occurring acetylated pseudoguaianolides and psilostachyin including their analogues were synthesized. The structure of semi-synthetic psilostachyin was also confirmed by X-ray crystallography. The anti-inflammatory potential of all the derivatives has been evaluated through in vitro expression of TNF-α, IL-1β and IL-6 in murine neutrophils.
Graphical abstractNaturally occurring acetylated pseudoguaianolides and spirolactone psilostachyin including their analogues were synthesized and evaluated for their anti-inflammatory potential.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Renu Chib, Bhahwal Ali Shah, Naveen Anand, Anjali Pandey, Kamini Kapoor, Sarang Bani, Vivek K. Gupta, Rajnikant, Vijay K. Sethi, Subhash Chandra Taneja,