| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1361956 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Triptolide γ-lactone and C-14 analogues were prepared and evaluated cytotoxity against human lung adenocarcinoma epithelial A549 cells and human colon adenocarcinoma HT-29 cells. γ-Lactone substructure and C-14 substituents affected the biological activities significantly.
Graphical abstractTriptolide γ-lactone and C-14 analogues were prepared and evaluated cytotoxity against A549 and HT-29 cells.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
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Authors
Yutaka Aoyagi, Yukio Hitotsuyanagi, Tomoyo Hasuda, Haruhiko Fukaya, Koichi Takeya, Ritsuo Aiyama, Takeshi Matsuzaki, Shusuke Hashimoto,