Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1361971 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Two series of triamino pyrimidines and a series of triamino pyridines have been synthesized and their structure–activity relationships evaluated for activity at the H4 receptor in competitive binding and functional assays. Small structural changes in these three hetereoaromatic cores influenced the functional activity of these compounds.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Steven P. Meduna, Brad M. Savall, Hui Cai, James P. Edwards, Robin L. Thurmond, Patricia M. McGovern,