Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1361972 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
A series of 6-azanaphthoquinone pyrrolo-annelated derivatives carrying different basic side chains have been synthesized. The antiproliferative activities of all compounds were evaluated on at least four different cell lines with Mitoxantrone as reference compound. Cytotoxic effects and DNA intercalation behavior were investigated.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Karem Shanab, Eva Schirmer, Eva Wulz, Barbara Weissenbacher, Sigrid Lassnig, Rita Slanz, Germana Fösleitner, Wolfgang Holzer, Helmut Spreitzer, Peter Schmidt, Babette Aicher, Gilbert Müller, Eckhard Günther,