| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1362200 | Bioorganic & Medicinal Chemistry Letters | 2011 | 7 Pages |
Abstract
Two series of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives exhibiting diverse functionality at rat MT1 and MT2 receptors are reported. Compounds 11f and 18b (MT1/MT2 agonist) have human microsomal intrinsic clearance comparable to ramelteon.
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Related Topics
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Organic Chemistry
Authors
Guiying Li, Hao Zhou, Yu Jiang, Holger Keim, Sidney W. Topiol, Suresh B. Poda, Yong Ren, Gamini Chandrasena, Darío Doller,