| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1362528 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
Radical 18F-fluoroarylation with fluorine-18-labelled arenediazonium chlorides has been successfully applied to the radiochemical synthesis of the dopamine D3-selective ligand SH 317 ([18F]8). SH 317 has been evaluated as a new PET ligand candidate by in vivo experiments.
Graphical abstractRadical 18F-fluoroarylation with fluorine-18-labelled arenediazonium chlorides has been successfully applied to the radiochemical synthesis of the dopamine D3-selective ligand SH 317 ([18F]8). SH 317 has been evaluated as a new PET ligand candidate by in vivo experiments.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
S.B. Höfling, S. Maschauer, H. Hübner, P. Gmeiner, H.-J. Wester, O. Prante, M.R. Heinrich,