| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1362557 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Histone deacetylase inhibitors with anticancer or anti-inflammatory activity bind to Class I or Class I and II HDAC enzymes. Here we compare selectivity of inhibitors of a Class II HDAC enzyme (HDAC6) and find one that retains high selectivity in macrophages.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Praveer K. Gupta, Robert C. Reid, Ligong Liu, Andrew J. Lucke, Steve A. Broomfield, Melanie R. Andrews, Matthew J. Sweet, David P. Fairlie,