Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1362777 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
Antagonist properties at α1-adrenoceptor subtypes, A, B and D for 1-[2-hydroxy-3-(4-phenylpiperazin-1-yl)-propyl]-2,4-dioxo-5,5-diphenylimidazolidine derivatives were evaluated in functional bioassays. Bremner's pharmacophores based SAR-studies were carried out.
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Authors
Jadwiga Handzlik, Heinz H. Pertz, Tilo Görnemann, Sven Jähnichen, Katarzyna KieÄ-Kononowicz,