| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1362978 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
Design, synthesis and cytotoxicity of several known and novel biurets against human breast cancer T47D cell line in comparison to doxorubicin are described. Biurets incorporating 2-methyl quinoline-4-yl and benzo[d]thiazol-2-ylthio moieties showed higher cytotoxicity and decreased cell viability in a concentration- and time-dependent manner.
Graphical abstractDesign, synthesis and cytotoxicity of several biurets substituted at N and N′ with different combination of R1 and R2 groups on human breast cancer T47D cell line are described.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shamileh Fouladdel, Ali Khalaj, Neda Adibpour, Ebrahim Azizi,