| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1362991 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
We have focused on the C5-modification of 2′-deoxyuridine with substituted heterocycles for bioactivity, such as antiviral or anticancer activity. Herein, we report a novel class of nucleoside analogues with perfluoroalkyltriazole moiety as an anticancer drug candidate.
Graphical abstractNovel synthesized perfluoroalkyltriazole-appended nucleosides exhibit anticancer activities against several cancer cell lines.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sun Min Park, Heeju Yang, Song-Kyu Park, Hwan Mook Kim, Byeang Hyean Kim,