| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1363331 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
A new phenylpropanoid conjugated iridoid together with four known congeners was isolated from Morinda morindoides, used for the therapy of malaria traditionally in some African countries, as anti-malarial principles through bioassay-guided separation. Furthermore, their absolute stereostructures were unambiguously established by a combination of modified Mosher’s method and chemical correlation.
Graphical abstractA new phenylpropanoid conjugated iridoid (1) together with four known congeners (2–5) was isolated from the leaves of Morinda morindoides as potent anti-malarial principles through bioassay-guided separation.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Satoru Tamura, Bruno Kilunga Kubata, Syamsurizal, Sawako Itagaki, Toshihiro Horii, Muzele Kalulu Taba, Nobutoshi Murakami,