| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1363380 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
A series of novel benzoxazole derivatives has been designed and shown to exhibit attractive JAK2 inhibitory profiles in biochemical and cellular assays, capable of delivering compounds with favorable PK properties in rats. Synthesis and structure–activity relationship data are also provided.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marc Gerspacher, Pascal Furet, Carole Pissot-Soldermann, Christoph Gaul, Philipp Holzer, Eric Vangrevelinghe, Marc Lang, Dirk Erdmann, Thomas Radimerski, Catherine H. Regnier, Patrick Chene, Alain De Pover, Francesco Hofmann, Fabienne Baffert,