| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1363395 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Polystyrene-supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ), a polymer-supported covalent coupling reagent, was successfully employed for the first time in the bioconjugation of an example hapten (phytanic acid derivative) to a carrier protein (bovine serum albumin (BSA)) within the context of immunogen preparation for antibody development. The ability of the prepared example phytanic acid derivative–BSA conjugate to bind an anti-phytanic acid antibody was confirmed using an enzyme-linked immunosorbent assay (ELISA).
Graphical abstractPolystyrene supported 2-isobutoxy-1-isobutoxycarbonyl-1,2-dihydroquinoline (PS-IIDQ), a polymer-supported covalent coupling reagent, was successfully employed for the first time in the bioconjugation of an example hapten (phytanic acid derivative) to a protein (bovine serum albumin (BSA)) within the context of immunogen preparation for antibody development.Figure optionsDownload full-size imageDownload as PowerPoint slide
