| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1363968 | Bioorganic & Medicinal Chemistry Letters | 2009 | 5 Pages |
Abstract
A series of amiloride derivatives modified at the 5-position of the pyrazine ring were evaluated as inhibitors of acid-sensing ion channel-3 (ASIC3), a novel target for the treatment of chronic pain.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Scott D. Kuduk, Christina N. Di Marco, Ronald K. Chang, Robert M. DiPardo, Sean P. Cook, Matthew J. Cato, Aneta Jovanovska, Mark O. Urban, Michael Leitl, Robert H. Spencer, Stefanie A. Kane, Mark T. Bilodeau, George D. Hartman, Mark G. Bock,