Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1364136 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
Prostate cancer is the most common cancer in men in Western countries, with a high incidence of bone metastasis. Ganoderic acid DM, with 5α-reductase inhibitory and androgen receptor (AR) binding activity, isolated from the ethanol extracts of Ganoderma lucidum, can inhibit prostate cancer cell growth and block osteoclastogenesis.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jie Liu, Jun Shiono, Kuniyoshi Shimizu, Akiko Kukita, Toshio Kukita, Ryuichiro Kondo,