Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1364139 | Bioorganic & Medicinal Chemistry Letters | 2009 | 4 Pages |
Abstract
Incorporation of the 2-cyano-1-en-3-one functionality into the A-ring of betulin and dihydrobetulin converted the non-cytotoxic molecules to potent apoptosis-inducing antiproliferative agents.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ali Koohang, Nathan D. Majewski, Erika L. Szotek, Aye Aye Mar, David A. Eiznhamer, Michael T. Flavin, Ze-Qi Xu,