Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1364384 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
We report the design and synthesis of equipotent PPARα/γ dual agonists starting from selective PPAR alpha agonist 1. In vivo data for 7 in the Zucker fa/fa rat are presented.
Graphical abstractWe report the design and synthesis of equipotent PPARα/γ dual agonists starting from the selective PPARα agonist 1. In vivo data for 7 in the Zucker fa/fa rat are presented.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Paul Martres, Nicolas Faucher, Alain Laroze, Olivier Pineau, Marie Helene Fouchet, Florent Potvain, Didier Grillot, Veronique Beneton,