Article ID Journal Published Year Pages File Type
1364393 Bioorganic & Medicinal Chemistry Letters 2008 5 Pages PDF
Abstract

The discovery and initial optimization of a novel anthranilic acid derived class of antibacterial agents has been described in a recent series of papers. This paper describes the discovery of 1-acylindazol-3-ols as a novel bioisostere of an anthranilic acid. The synthesis and structure–activity relationships of the indazol bioisosteres are described herein.

Graphical abstractThis paper describes the discovery of 1-acylindazol-3-ols as a novel bioisostere of an anthranilic acid. The synthesis and structure–activity relationships of the indazol bioisosteres are described herein.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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