| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1364738 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
Seven sesterterpene sulfates (1–7) were isolated from the tropical sponge Dysidea sp. and their inhibitory activities against isocitrate lyase (ICL) from Candida albicans were evaluated. Among the isolated natural products compound 6 and 7 were found to be strong ICL inhibitors. The isolated compounds (1–7) also showed potent antibacterial effect against Bacillus subtilis and Proteus vulgaris, but did not display antifungal activity.
Graphical abstractThe isolation and bioactivity of seven sesterterpene sulfates are described.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dongha Lee, Jongheon Shin, Kyung-Mi Yoon, Tae-Im Kim, So-Hyoung Lee, Hyi-Seung Lee, Ki-Bong Oh,