| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1364792 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
We synthesized all of the monomethoxycoumarins, 5-alkoxycoumarins and their derivatives, and investigated their nematicidal activity against the phytopathogenic nematode, Bursaphelenchus xylophilus. Among the compounds, 5-ethoxycoumarin showed the highest nematicidal activity. Furthermore, 5-ethoxycoumarin was comparatively harmless against both the brine shrimps, Artemia salina, and the Japanese killifish, Oryzias latipes.
Graphical abstractAll monomethoxycoumarins and several 5-alkoxycoumarins were examined nematicidal activity and environment safety using crustacean and fish. Among them 5-alkoxycoumarins produced an excellent result even though their simple skeletons.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kazuto Takaishi, Minoru Izumi, Naomichi Baba, Kazuyoshi Kawazu, Shuhei Nakajima,