| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1364811 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
An exploratory SAR study on a series of non-apamin-displacing 4-(aminomethylaryl)pyrazolopyrimidine KCa channel blockers is described, and their selectivity against KCa channel subtypes is reported. The aminomethylthiophene derivative 24, was the most potent analog identified in the series.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Robert G. Gentles, Shuanghua Hu, Yazhong Huang, Katherine Grant-Young, Michael A. Poss, Charles Andres, Tracey Fiedler, Ronald Knox, Nicholas Lodge, C. David Weaver, David G. Harden,