| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1364975 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
Inhibition of the PHD2 enzyme has been associated with increased red blood cell levels. From a screening hit, a series of novel hydroxyl-thiazoles were developed as potent PHD2 inhibitors.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Christopher M. Tegley, Vellarkad N. Viswanadhan, Kaustav Biswas, Michael J. Frohn, Tanya A.N. Peterkin, Catherine Chang, Roland W. Bürli, Jennifer H. Dao, Henrike Veith, Norma Rogers, Sean C. Yoder, Gloria Biddlecome, Philip Tagari, Jennifer R. Allen,