Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1365173 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
The synthesis and the biological evaluation of the anti-HIV-1 activity of TSAO-Boc3T (8) are described. The computational analysis showed that N-3 Boc group promotes new interactions in the binding site of the enzyme leading to a good inhibitory value.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Cyrille Tomassi, Albert Nguyen Van Nhien, José Marco-Contelles, Jan Balzarini, Christophe Pannecouque, Erik De Clercq, Elena Soriano, Denis Postel,