Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1365179 | Bioorganic & Medicinal Chemistry Letters | 2008 | 5 Pages |
Abstract
A method for the preparation of oligomers by linking chromophore units is described. Specifically, the synthesis of chromophore units having a protected-hydroxyl group and a phosphoramidite function is described, along with a method to link several units using solid-phase phosphite-triester protocols.
Graphical abstractThe synthesis of oligomers having several DNA-intercalating units linked by phosphodiester bonds is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Anna Aviñó, Isabel Navarro, Josep Farrera-Sinfreu, Miriam Royo, Juan Aymamí, Antonio Delgado, Amadeu Llebaria, Fernando Albericio, Ramon Eritja,