Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1365187 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
A series of novel dispirooxindolopyrrolizidine derivatives have been synthesized through 1,3-dipolar cycloaddition reaction of azomethine ylide generated from proline and isatin with the dipolarophile (E)-2-arylidine-1-keto carbazoles. The synthesized cycloadducts were evaluated for antimicrobial activities. Compounds 7d and 7e showed relatively good antibacterial and antifungal activities.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Govindasami Periyasami, Raghavachary Raghunathan, Gangadharan Surendiran, Narayanasamy Mathivanan,