Synthesis of novel analogues of (+)-varitriol via olefin cross-metathesis reaction

Novel analogues of (+)-varitriol have been synthesized via olefin cross-metathesis reaction using Grubb’s catalyst. Newly synthesized compounds were screened for cytotoxicity and they showed mild activity against RAW264.7 and HT29 cell lines.

Graphical abstractNovel analogues of (+)-varitriol have been synthesized via olefin cross-metathesis reaction using Grubb’s catalyst. Newly synthesized compounds were screened for cytotoxicity.Figure optionsDownload full-size imageDownload as PowerPoint slide