| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1365367 | Bioorganic & Medicinal Chemistry Letters | 2008 | 6 Pages |
Abstract
This Letter describes the design, synthesis, and biological evaluation of novel 3-indole sulfonamides as potent non-nucleoside reverse transcriptase inhibitors (NNRTIs) with balanced profiles against common HIV RT mutants K103N and Y181C.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhijian Zhao, Scott E. Wolkenberg, Meiqing Lu, Vandna Munshi, Gregory Moyer, Meizhen Feng, Anthony V. Carella, Linda T. Ecto, Lori J. Gabryelski, Ming-Tain Lai, Sridar G. Prasad, Youwei Yan, Georgia B. McGaughey, Michael D. Miller, Craig W. Lindsley,