| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1365374 | Bioorganic & Medicinal Chemistry Letters | 2008 | 4 Pages |
Abstract
A novel series of 1-(2-phenoxyphenyl)methanamines is disclosed, which possess selective dual 5-HT and NA reuptake pharmacology. Analogues with good human in vitro metabolic stability, hERG selectivity and passive membrane permeability were identified.
Graphical abstractA novel series of 1-(2-phenoxyphenyl)methanamines are disclosed, which possess selective dual 5-HT and NA reuptake pharmacology. Analogues with good human in vitro metabolic stability, hERG selectivity and passive membrane permeability were identified.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gavin A. Whitlock, Julian Blagg, Paul V. Fish,