Article ID Journal Published Year Pages File Type
1365411 Bioorganic & Medicinal Chemistry Letters 2008 6 Pages PDF
Abstract

A new series of benzene and isoquinoline sulfonamide derivatives were synthesized by nucleophilic displacement reaction on benzene and isoquinoline sulfonyl chlorides by substituted amines (primary and secondary). The title compounds were evaluated for antimalarial activity against Plasmodium falciparum in vitro and showed MIC in the range of 2–50 μg/mL.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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