Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1365411 | Bioorganic & Medicinal Chemistry Letters | 2008 | 6 Pages |
Abstract
A new series of benzene and isoquinoline sulfonamide derivatives were synthesized by nucleophilic displacement reaction on benzene and isoquinoline sulfonyl chlorides by substituted amines (primary and secondary). The title compounds were evaluated for antimalarial activity against Plasmodium falciparum in vitro and showed MIC in the range of 2–50 μg/mL.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Maloy Kumar Parai, Gautam Panda, Kumkum Srivastava, Sunil Kumar Puri,