| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1365512 | Bioorganic & Medicinal Chemistry Letters | 2007 | 6 Pages |
Abstract
A series of amino-caprolactam sulfonamides were developed from a screening hit. Compounds with good in vitro and in vivo γ-secretase activity are reported.
Graphical abstractA series of amino-caprolactam sulfonamides were developed from a screening hit. Compounds with good in vitro and in vivo γ-secretase activity are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Michael F. Parker, Joanne J. Bronson, Donna M. Barten, Jason A. Corsa, Wengsheng Du, Kevin M. Felsenstein, Valerie L. Guss, Darcy Izzarelli, Alice Loo, Kate E. McElhone, Larry R. Marcin, Ramesh Padmanabha, Roger Pak, Craig T. Polson, Jeremy H. Toyn,