| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1365525 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
Two new abietane-type diterpenes, taxodistines A (1) and B (2), have been isolated by the guidance of inhibitory effect of tubulin polymerization from the fruits of Taxodium distichum and the structures were elucidated by using 2D NMR data. Taxodistine B (2) showed inhibition of tubulin polymerization.
Graphical abstractTwo new abietane-type diterpenes, taxodistines A (1) and B (2), have been isolated by the guidance of inhibitory effect of tubulin polymerization from the fruits of Taxodium distichum and the structures were elucidated by using 2D NMR data. Taxodistine B (2) showed inhibition of tubulin polymerization.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yusuke Hirasawa, Emi Izawa, Yosuke Matsuno, Nobuo Kawahara, Yukihiro Goda, Hiroshi Morita,