| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1365546 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
The synthesis of 6-epi-COTC, a diastereoisomer of Streptomyces metabolite 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC), is described. The anti-cancer activities of the novel analogue, in racemic and enantiomerically pure forms, are presented.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Claire L. Arthurs, James Raftery, Helen L. Whitby, Roger C. Whitehead, Natasha S. Wind, Ian J. Stratford,