Article ID Journal Published Year Pages File Type
1365684 Bioorganic & Medicinal Chemistry Letters 2007 4 Pages PDF
Abstract

The A,B-ring-truncated OSW saponin analogs (1, 18a, and 18b) were synthesized. These greatly simplified trans-hydrindane disaccharides retained considerable inhibitory activity against the growth of HeLa and Jurkat T cells (IC50 = 0.8–21.1 μM).

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , , ,