| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1366061 | Bioorganic & Medicinal Chemistry Letters | 2007 | 6 Pages |
Abstract
Novel oxazolidinone derivatives of the lead compound RBx 8700, containing methylene oxygen- and methylene sulfur-linked substituents at the C5-position, were synthesized. Antibacterial screening of these compounds against a panel of resistant and susceptible Gram-positive and fastidious Gram-negative bacteria gave compounds 2 and 4 as new antibacterial agents.
Graphical abstractNovel oxazolidinone derivatives of the lead compound RBx 8700 containing methylene oxygen- and methylene sulfur-linked substituents at C5-position were synthesized and their biological activity reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sonali Rudra, Fnu Sangita, Arti Gujrati, Manisha Pandya, Pragya Bhateja, Tarun Mathur, Smita Singhal, Ashok Rattan, Mohammed Salman, Biswajit Das,