Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1366186 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
This paper describes a divergent de novo synthesis of 2-(2,3-anhydro-β-dribofuranosyl)thiazole-4-carboxamide (2′,3′-anhydro-tiazofurin) and the corresponding α- and β-homo-C-nucleosides, as well as evaluation of their antitumour activities in vitro.
Graphical abstractNovel tiazofurin derivatives, 2′,3′-anhydro-tiazofurin (2) and the corresponding β-(3) and α-(17) homo-C-nucleosides, have been synthesized and evaluated for their in vitro antitumour activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mirjana Popsavin, Saša Spaić, Miloš Svirčev, Vesna Kojić, Gordana Bogdanović, Velimir Popsavin,