| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1366238 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
A number of compounds bearing a quaternary ammonium moiety were found to be antagonists with nanomolar binding affinity for the chemokine receptor-2. The structure–activity relationships in the series are described herein along with some detailed characterization of the interesting compounds.
Graphical abstractA number of compounds bearing a quaternary ammonium moiety were found to be antagonists with nanomolar binding affinity for the chemokine receptor-2. The structure–activity relationships in the series are described herein along with some detailed characterization of the interesting compounds.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Authors
Bharat Lagu, Chrissy Gerchak, Meng Pan, Cuifen Hou, Monica Singer, Ravi Malaviya, Michele Matheis, Gil Olini, Druie Cavender, Michael Wachter,