Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1366573 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
Fluorinated substrate analogs were synthesized and incubated with rat liver 3-hydroxyacyl-CoA dehydrogenase, which reveals that the formation of an enolate intermediate is required for the reaction catalyzed by the enzyme.
Graphical abstractFluorinated substrate analogs were synthesized and incubated with rat liver 3-hydroxyacyl-CoA dehydrogenase, which reveals that the formation of an enolate intermediate is required for the enzymatic reaction.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaojun Liu, Guisheng Deng, Xiusheng Chu, Nan Li, Long Wu, Ding Li,