| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1366574 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
In combination with chemical modifications, bioassays, and computational simulation techniques, C-2 benzoylthio, and benzylthio taxoids were synthesized, biologically evaluated, and their binding conformations rationalized, in order to probe the interaction of taxane molecule with β-tubulin.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lei Wang, Ana A. Alcaraz, Ruth Matesanz, Chun-Gang Yang, Isabel Barasoain, J. Fernando Díaz, Ye-Zhi Li, James P. Snyder, Wei-Shuo Fang,