| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1366725 | Bioorganic & Medicinal Chemistry Letters | 2007 | 6 Pages |
Abstract
2-Alkylbenzimidazoles bearing a N-phenylpyrrole moiety 10a and 10g inhibited [125I] AngII-binding affinity to AT1 receptor at nanomolar level and evaluation in spontaneously hypertensive rats showed that 10a is an orally active AT1 receptor antagonist.
Related Topics
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Chemistry
Organic Chemistry
Authors
Jin Yi Xu, Yi Zeng, Qian Ran, Zhen Wei, Yi Bi, Qian Hui He, Qiu Juan Wang, Song Hu, Jing Zhang, Ming Yue Tang, Wei Yi Hua, Xiao Ming Wu,