Article ID Journal Published Year Pages File Type
1366823 Bioorganic & Medicinal Chemistry Letters 2007 4 Pages PDF
Abstract

In this study, a series of novel phenyl- and benzimidazole-substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, Methicillin-resistant S. aureus (MRSA), Escherichia coli, Candida albicans, and Candida krusei. Compound 6g exhibited the most potent antibacterial activity with lowest MIC values of 3.12 and 6.25 μg/mL against S. aureus and MRSA, respectively.

Graphical abstractThe synthesis and antibacterial effects of benzyl ethers were reported.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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