Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1366823 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
In this study, a series of novel phenyl- and benzimidazole-substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, Methicillin-resistant S. aureus (MRSA), Escherichia coli, Candida albicans, and Candida krusei. Compound 6g exhibited the most potent antibacterial activity with lowest MIC values of 3.12 and 6.25 μg/mL against S. aureus and MRSA, respectively.
Graphical abstractThe synthesis and antibacterial effects of benzyl ethers were reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Özden Özel Güven, Taner Erdoğan, Hakan Göker, Sulhiye Yıldız,