Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1366829 | Bioorganic & Medicinal Chemistry Letters | 2007 | 7 Pages |
Abstract
A new M2/M1 quantitative structure-selectivity relationship (QSSR) model of piperidinyl piperidine derivatives as muscarinic M2 subtype receptor antagonists was constructed, discussed, and examined. This model could provide solid basis for designing novel molecules with higher antagonistic selectivity to muscarinic receptors.
Related Topics
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Chemistry
Organic Chemistry
Authors
Yin-Yao Niu, Li-Min Yang, Ke-Min Deng, Jian-Hua Yao, Liang Zhu, Cong-Ying Chen, Min Zhang, Jin-E Zhou, Tian-Xiang Shen, Hong-Zhuan Chen, Yang Lu,