| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1366835 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
Substituted 1-hydroxy-4,4-dialkyl-3-oxo-3,4-dihydronaphthalene benzothiadiazine derivatives were investigated as inhibitors of genotype 1 HCV polymerase. Structure–activity relationship patterns for this class of compounds are discussed. It was found that the saturated alkane dialkyl units provided the most active analogs.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
A. Chris Krueger, Darold L. Madigan, Brian E. Green, Douglas K. Hutchinson, Wen W. Jiang, Warren M. Kati, Yaya Liu, Clarence J. Maring, Sherie V. Masse, Keith F. McDaniel, Tim R. Middleton, Hongmei Mo, Akhteruzzaman Molla, Debra A. Montgomery,