| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1366953 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
Aromatase is a particularly good target in the treatment of estrogen receptor positive breast cancer. Novel carbon-11 labeled sulfonanilide analogues, N-[11C]methyl-N-(2-alkyloxy-4-nitrophenyl)-methanesulfonamides ([11C]3a–f, alkyl = propyl, isopropyl, 1-ethyl-propyl, cyclopentyl, cyclohexyl, and cyclohexylethyl), were designed and synthesized as potential PET agents for imaging of aromatase in breast cancer.
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Related Topics
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Chemistry
Organic Chemistry
Authors
Min Wang, Gabrielle Lacy, Mingzhang Gao, Kathy D. Miller, George W. Sledge, Qi-Huang Zheng,