| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367073 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
The synthesis of three phosphoglycerols is described, one of which contains the previously unknown phosphonoglycerol headgroup. The surface tension-lowering capabilities of synthetic lung surfactant mixtures containing the PG analogs were measured on the pulsating bubble surfactometer and compared to known controls. The PG-containing mixtures exhibited superior surface tension-lowering properties indicating the significant potential of these analogs as components in synthetic exogenous lung surfactants.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Robert H. Notter, Zhongyi Wang, Zhengdong Wang, Jason A. Davy, Adrian L. Schwan,