Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1367074 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
The design, synthesis, and biological evaluation of the 2-phenyl-isoindole-1,3-diones will be discussed. Detailed modeling studies with X-ray support were used to understand the ligand binding orientation and observed selectivity.
Graphical abstractThe design, synthesis and biological evaluation of the 2-phenyl-isoindole-1,3-diones will be discussed. Detailed modeling studies with X-ray support were used to understand the ligand binding orientation and observed selectivity.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
John W. Ullrich, Rayomand J. Unwalla, Robert R. Singhaus Jr., Heather A. Harris, Richard E. Mewshaw,