| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1367082 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
A bisdesmosidic steroidal saponins library, composed of 16 novel kryptogenin glycosides, was set up via six random glycosylation procedures, wherein two compounds showed their antitumor activity against HeLa cell in the preliminary pharmacological research.
Graphical abstractA library of 16 novel bisdesmosidic kryptogenyl saponins was built for investigation of antitumor activity, wherein two compounds showed inhibition against HeLa cells (IC50 = 4.25 μM for 7a and 8.36 μM for 7i).Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yang Liu, Dong-Mei Zhao, Xue-Hua Lu, Hui Wang, Hong Chen, Ying Ke, Ling Leng, Mao-Sheng Cheng,